EVOLUTIONARY ACCOUNT OF ECP:

1. During 1950’s: Kantrowitzs first described the principle: "phase shift diastolic augmentation". In 1953, physicians and      physicists at Harvard and elsewhere related this principle to oxygen consumption and workload. This understanding      led to the concept of mechanically induced “cardiac assistance” for patients with low output syndrome, especially      cardiogenic shock.

2. During 1960’s: Beginning in the 1960’s research on mechanically induced “cardiac assistance” followed two distant      paths, one involved the use of balloon positioned inside the descending thoracic aorta that would inflate during      diastole and deflate at the onset of systole, and another of the vascular beds in the lower limbs. The first came to be      known as the intra-aortic balloon (IABP). The second evolved as to what is now referred as ECP. These early      systems were somewhat primitive by today’s standards. But both forms of Counter pulsation clearly demonstrated      the potential for increasing survival of the patient with myocardial infarction cardiogenic shock as well as for relief of      angina pectoris.

     In 1960’s, Three groups (Birtwell and Soroff, Dennis, and Osborn) independently developed hydraulically activated      external counter pulsation devices and found the technique effective in impproving survival after myocardial infarction      complicated by cardiogenic shock. Initial experience with a crude external counter pulsation device used in stable      angina saw relief of angina symptoms with angiographic evidence of increased vascularity.



     Early hydraulic system for ECP eventually gave way to pneumatics. This, along with refinements of the compression      element of the system, helped to improve outcomes and patient comfort. The national institute of health (NIH) in the      United States played a significant role in the modern ECP systems by advocating the addition of a second cuff and      the use of a sequential cuff inflation to increase the amount of blood being returned to the heart and as a result      diastolic augmentation.

3. During 1970’s: Before 1970’s all ECP’s were “nonsequenced” pulsation. During the1970’s, Zheng and Associates at     Sun Yat Sen University in china reported on a newly designed 3 stage pneumatic pulsation system. In this trial the     effect provided long term symptomatic relief and minimal relapse, following 36 hours of treatment. Their clinical     experience     led to the installation of more than 1,500 external counter pulsation units in China during the past 15 years     leading to     the development and refinement of the ECP technique and device.

 
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